CHLOROFORM
SYNONYMS:
CHLOROFORME
(French); CHLOROFORMO (Spanish); EEC No. 602-006-00-4; EINECS No. 200-663-8;
FORMYL TRICHLORIDE; FREON 20; METHANE TRICHLORIDE; METHANE, TRICHLORO-;
METHENYL TRICHLORIDE; METHYL TRICHLORIDE; NCIC02686; R 20 (REFRIGERANT); TCM;
TRICHLOROFORM; TRICHLOROMETHANE
IDENTIFICATION:
CAS:
67-66-3
DOT ID:
UN1888
Hazard class or Division:
6.1 (POISONOUS/TOXIC MATERIALS)
ERG Guide:
151
Formula:
CCl3H
RTECS No:
FS9100000
Properties:
Clear,
colorless, watery liquid. Sweet ether-like odor. Sinks in water; slightly
soluble. Toxic and irritating gases of phosgene and hydrogen chloride are
produced when heated. Vapors are heavier than air; will collect in low areas.
Uses:
Solvent;
cleansing agent.
HEALTH & SAFETY INFORMATION
• IDLH:
500
ppm. Potential human carcinogen.
• IARC:
Group
2B, possible human carcinogen; human evidence, limited; animal evidence,
sufficient.
• NTP:
Anticipated
human carcinogen.
•
NCI:
Clear evidence, carcinogenesis (mouse, rat).
• Odor threshold:
5067 mg/m3.
•
OSHA Table Z-1 Air Contaminant
• NIOSH Criteria Document
: NIOSH 75-114
•
Causes irritation of the eyes, skin, and respiratory tract. May affect the
central nervous system, liver, and kidneys. The effects may be delayed.
Long-term exposure may include sluggishness, depression, hallucinations, loss
of appetite, fatigue, and liver and kidney damage. Chloroform is a suspected
carcinogenic agent because high levels cause kidney, liver, and thyroid cancer
in rats and mice. Abnormal sperm found in laboratory tests.
Exposure Limits:
•
ACGIH TLV: 10 ppm TWA; confirmed animal carcinogen with unknown relevance to
humans.
•
OSHA PEL: 50 ppm/240 mg/m3 ceiling limit
•
NIOSH REL: 2 ppm/9.78 mg/m3 60 min. STEL. Reduce exposure to lowest feasible
concentration.
•
DFG MAK: 0.5 ppm/2.5 mg/m3, suspected carcinogen
Respirator:
At
any concentrations above the NIOSH REL, or where there is no REL, at any
detectable concentration:
SCBAF:PD,PP
(any self-contained breathing apparatus that has a full facepiece and is
operated in a pressure-demand or other positivepressure mode)
P
SAF:PD,PP:ASCBA (any suppliedair respirator that has a full
facepiece and is operated in a pressure-demand or other positive-pressure mode
in combination with an auxiliary self-contained breathing apparatus operated in
a pressure-demand or other positive-pressure mode).
Escape:
GMFOV [any airpurifying, full-facepiece
respirator (gas mask) with a chin-style, front- or back-mounted organic vapor
canister]
P
SCBAE (any appropriate escape-type,
selfcontained breathing apparatus).
Reactivity:
Decomposes
in the presence of excess water, sunlight, or high temperatures, forms highly
toxic and corrosive phosgene and hydrogen chloride. Strong alkalies like lye
and potassium hydroxide decompose chloroform to chloride salts and formates.
Can become explosive in the presence of strong alkalies and water. In contact
with water and high temperatures, becomes corrosive; attacks iron and other
metals. Incompatible with acetone, aluminum, Strong oxidizers, potassium,
sodium, chemically active metals, and strong bases. Attacks plastics and
rubber. Can accumulate static electrical charges.
FIRE INFORMATION:
If material or contaminated runoff enters waterways, notify
downstream users of potentially contaminated water.
Hazard Classifications:
Health Hazard (Blue)
. . . . . . . . . . . . . . 2
Flammability (Red)
. . . . . . . . . . . . . . . 0
Reactivity (Yellow)
. . . . . . . . . . . . . . . . 0
FIRST AID:
Move
victim to fresh air. Call emergency medical care. Apply artificial respiration
if victim is not breathing. Do not use mouth-to-mouth method if victim ingested
or inhaled the substance; induce artificial respiration with the aid of a
pocket mask equipped with a one-way valve or other proper respiratory medical
device. Administer oxygen if breathing is difficult. Remove and isolate
contaminated clothing and shoes. In case of contact with substance, immediately
flush skin or eyes with running water for at least 20 minutes. For minor skin
contact, avoid spreading material on unaffected skin. Keep victim warm and
quiet. Effects of exposure (inhalation, ingestion, or skin contact) may be
delayed. Ensure that medical personnel are aware of the material(s) involved,
and take precautions to protect themselves.
ENVIRONMENTAL REGULATIONS
•
Clean Air Act: Hazardous Air Pollutants (Title I, Part A, Section 112);
Accidental Release Prevention/Flammable substances, (Section 112[r], Table 3),
TQ = 20,000 lb (9,080kg).
•
Clean Water Act: Section 311 Hazardous Substances/RQ (same as CERCLA); Section
307 Priority Pollutants; Section 313 Priority Chemicals; Toxic Pollutant
(Section 401.15).
•
EPA Hazardous Waste Number (RCRA No.): U044; D022.
•
RCRA Toxicity Characteristic (Section 261.24): Maximum Concentration of
Contaminants, regulatory level, 6.0 mg/L
•
RCRA Section 261 Hazardous Constituents
•
RCRA Land Ban Waste
•
RCRA Universal Treatment Standards: Wastewater (mg/L), 0.046; Nonwastewater
(mg/kg), 6.0.
•
RCRA Ground Water Monitoring List: Suggested test method(s) (PQL
μ
g/L): 8010(0.5); 8240(5).
•
Safe Drinking Water Act: Priority List (55 FR 1470).
•
EPCRA Section 302 Extremely Hazardous Substances: TPQ = 10,000 lb (4540 kg).
•
EPCRA Section 304: Reportable Quantity (RQ): CERCLA, 10 lb (4.54 kg).
•
EPCRA Section 313: Form R
de
minimis
concentration
reporting level: 0.1%.
•
California LOL: BCDEGIKMNOQR
•
WHMIS, Ingredients Disclosure List (Canada): 0.1%